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A disorganized storm system will coalesce over the nation’s midsection on Thursday. As a result, significant, wind-driven snow will develop on Thursday in the upper Midwest and spread into the Great Lakes region. Parts of the Midwest and Northeast could experience late-week freezing rain. The coldest air of the season will trail the Midwestern storm, with temperatures during the weekend and early next week possibly falling to 0° or below as far south as the Ohio and middle Mississippi Valleys.